[Ethnopharmacology of Amygdalus Lycioides Spach var. Horrida in east of Esfahan in Iran]

Background: Documenting of indigenous knowledge related to traditional medicine often leads to discovery of new drugs and prevent from destruction and forgotten it

Objective: Documentation of medicinal use of Amygdalus lycioides Spach var. horrida in traditional medicine of local people Naein, Khoor and Biabanak county in northeast of Esfahan in Iran

Methods: Ethnopharmacological information was collected using snowball sampling, Participant Observation and semi-structured interviews from 120 informants. The question of the interviews includes demography of informants, plant local name, medicinal properties, symptoms of the disease, used part, mode of application, route of administration and effectiveness of medicine, Adverse Drug Reaction, Medications or alternatives for treatment, In addition, it was also investigated about whether the informants used it for therapeutic purposes

Results: In Traditional medicine of Case study the A.lycioides are used in the treatment of disease such as diabetes, blood fat, hypotensive, Inflammation of the prostate, durectic, kidney stone, pain, Constipation, Colds and asthma. 98% of informants have reached the desired medicinal properties using aerial parts of the species

Conclusion: This study report Medicinal properties of A. lycioides treating blood fat, Inflammation of the prostate, durectic, and kidney stone for the first time. Also the result shows that for medicinal uses it is not necessary to use the root of plant

[Effects of estrogen progesterone on endometrial glycocalyx expression in superovulated mice in the implantation window time]

It has been reported that apical glycocalyx expression of uterine affects embryo implantation. The aim of this study was to determine endometrial glycocalyx and endometrial thickness after estrogen and progesterone injection in hyperstimulated mice at luteal phase. Adult male and female mice were used for induction of pesudopregnancy. The mice were divided into two groups experimental and control groups. Female mice in the experimental group were superovulated and were then mated with vasectomised mice to induce psudopregnancy Experimental group based on hormone injection was subdivided into five groups 1] Estrogen, 2] Progesterone, 3] Estrogen + Progesterone, 4] Antiprogesterone + Estrogen, 5] Sham. Pesudopregnancy in the control group was achieved without any hyperstimulation. The uterines of all groups were collected after 4.5 days of pregnancy and prepared for the assessment of endometrial thickness and endometrial glycocalyx expression. The results showed that estrogen and progesterone injection increased the intensity of PAS reaction, whereas progesterone decreased this. Also our results showed that the endometrial thickness in the sham group was the highest and in the progesterone group was the lowest Our results showed that addition of estrogen to progesterone, compared to P supplementation alone, provided appropriate endometrial conditions to embryo implantation. Hence combination of estrogen and progesterone injection as luteal support hormones can be used in IVF protocols

Risk factors of Atopic dermatitis in Shahrekord schoolchildren

Atopic dermatitis is one of the common skin diseases of childhood that creates considerable side effects on patients, their families and the health care system. This study was carried out to identify both prevalence rate and risk factors of the disease in Shahrekord schoolchildren in 2003. In a cross-sectional study from all Shahrekord schoolchildren. 1500 students [750 female, 750 male] were randomly selected and the questionnaires of atopic dermatitis were distributed among the selected students and then collected after being filled by their parents then all selected students were examined by a general physician. Suspected students were examined by a dermatologist and an ophthalmologist. The serum IgE of students with any evidence of AD was then serologically tested and the collected data were analyzed with both X[2] and student-t test. The mean ages of students participated in the survey was 9.2 +/- 1.4 years. According to AD criteria, the prevalence rate was 2.1 percent [32 students]. There was no significant statistical relationship between sex and age with atopic dermatitis prevalence rate, but there was significant statistical relationship between AD prevalence rate and signs and symptoms of asthma, allergic renitis, family history of the atopic dermatitis and atopy [p<0.05]. Our results showed that atopic dermitis was more frequently seen in those individual with asthma, allergic renitis, familial history for atopic eczema or familial history for atopic dermitis. But no relationship between atopic dermitis and age as well as sex was observed

[ response of tinea capitis to treatment with a two-week oral terbinafine]

Dermatophytosis is a superficial infection caused by a group of closely related fungi, Dermatophytes. Trichophyton and Microsporum species are only Dermatophytes with the capacity of invasion to hair [tinea capitis]. Terbinafine, one of the anti-dermatophytosis drugs which is recommended for the treatment of this infection for a period of 2 to 6 weeks depends on the sensitivity and severity of the infection. The best duration of therapy is not clear yet. Therefore, the aim of this study was to evaluate the response of tinea capitis to treatment with a two-week oral terbinafine regimen. We tested 29 clinical isolates of dermatophytes using both direct smear [%10 KOH solutions] and culture [saburow and dextrose agar medium]. Nine cases were Microsporum and twenty cases were Trichophytons. Patients were treated with oral terbinafine for two weeks and then tested clinically by the same method three times during 2.5 months for detection of the fungi. SPSS software and Fisher-test were used for data analysis. At the end of treatment period, direct Smear showed that 7 cases of ectotria and culture was negative for 20 [100%] cases of Trichophytons and positive for 9 [100%] cases of Microsporums. A two-week oral terbinafine regimen is recommended for treatment of Trichophyton infections but not for Microsporum infections